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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Fructuoso Noa | 0.971 | 1886 | |
| 2 | Fructuoso Noa | 1.186 | 1888 | |
| 3 | Jorge Vélez# | 1.325 | 1888 | |
| 4 | Flaminio Martínez | 1.337 | 1884 | |
| 5 | Cleto Correa# | 1.368 | 1892 | |
| 6 | Eduardo Resto | 1.373 | 1884 | |
| 7 | Héctor López | 1.386 | 1880 | |
| 8 | Heliodoro Pérez | 1.446 | 1886 | |
| 9 | Heliodoro Pérez | 1.462 | 1885 | |
| 10 | Flaminio Martínez | 1.479 | 1880 | |
| 10 | Pandolfo Ortega# | 1.479 | 1888 | |
| 12 | Flaminio Martínez | 1.481 | 1882 | |
| 13 | Juan Padilla | 1.482 | 1878 | |
| 14 | Héctor López | 1.484 | 1886 | |
| 15 | Juan Martínez# | 1.489 | 1892 | |
| 16 | Fructuoso Noa | 1.541 | 1891 | |
| 17 | Sixto Almaguer | 1.563 | 1879 | |
| 18 | Flaminio Martínez | 1.573 | 1885 | |
| 19 | Pandolfo Ortega# | 1.636 | 1884 | |
| 20 | Ernesto Cruz | 1.664 | 1878 | |
| 21 | Ludovico Andrade | 1.671 | 1883 | |
| 22 | Flaminio Martínez | 1.706 | 1888 | |
| 23 | Luis Mejía | 1.707 | 1878 | |
| 24 | José Barreto# | 1.714 | 1892 | |
| 25 | Ignacio Barbosa | 1.715 | 1878 | |
| 26 | Froilán Carrillo | 1.737 | 1879 | |
| 27 | Juan Echeverría# | 1.752 | 1888 | |
| 28 | Diego López | 1.760 | 1880 | |
| 29 | Milcíades Gallegos | 1.766 | 1888 | |
| 30 | Zeferino Duque | 1.769 | 1882 | |
| 31 | Jesus Umana | 1.776 | 1880 | |
| 32 | Pío Martínez | 1.784 | 1880 | |
| 33 | Ernesto Cruz | 1.813 | 1885 | |
| 34 | Ludovico Andrade | 1.819 | 1880 | |
| 35 | Jesus Umana | 1.860 | 1878 | |
| 36 | Romualdo Baca | 1.873 | 1888 | |
| 37 | Flaminio Martínez | 1.894 | 1883 | |
| 38 | Fructuoso Noa | 1.908 | 1889 | |
| 39 | Federico Escobedo | 1.918 | 1883 | |
| 40 | Héctor López | 1.929 | 1881 | |
| 41 | Cleto Correa# | 1.938 | 1889 | |
| 41 | Raúl Torres | 1.938 | 1888 | |
| 43 | Ernesto Cruz | 1.950 | 1884 | |
| 44 | Zenobio Rodríguez# | 1.960 | 1891 | |
| 45 | Zeferino Duque | 1.974 | 1885 | |
| 46 | Héctor López | 1.976 | 1885 | |
| 47 | Afrodisio García | 1.989 | 1888 | |
| 48 | Zenobio Rodríguez# | 1.995 | 1890 | |
| 49 | Fructuoso Noa | 2.017 | 1887 | |
| 50 | Federico Hernández# | 2.019 | 1888 | |
| 50 | Miguel Luna | 2.019 | 1880 | |
| 50 | Juan Sanabria | 2.019 | 1880 | |
| 53 | Milcíades Gallegos | 2.021 | 1889 | |
| 54 | Fructuoso Noa | 2.045 | 1885 | |
| 54 | Julio Alvarado | 2.045 | 1886 | |
| 56 | Romualdo Baca | 2.053 | 1892 | |
| 56 | Eduardo Resto | 2.053 | 1882 | |
| 58 | Pío Martínez | 2.060 | 1890 | |
| 59 | Eduardo Resto | 2.067 | 1880 | |
| 59 | Juan Padilla | 2.067 | 1881 | |
| 61 | Fructuoso Noa | 2.070 | 1892 | |
| 62 | José Barreto# | 2.073 | 1888 | |
| 63 | Diego Martín | 2.077 | 1886 | |
| 64 | Fernando Rodríguez | 2.084 | 1888 | |
| 65 | Efraín Rodríguez | 2.086 | 1882 | |
| 66 | Julio Alvarado | 2.111 | 1883 | |
| 66 | Héctor López | 2.111 | 1884 | |
| 68 | Gaudencio Delgado | 2.112 | 1888 | |
| 69 | Bernal Echevana | 2.113 | 1892 | |
| 70 | Francisco Cueva# | 2.117 | 1891 | |
| 71 | Premislao Isla | 2.123 | 1889 | |
| 72 | Cleto Correa# | 2.133 | 1891 | |
| 72 | Ignacio Barbosa | 2.133 | 1882 | |
| 74 | Romualdo Baca | 2.155 | 1890 | |
| 75 | Fernando Rodríguez | 2.162 | 1890 | |
| 76 | Héctor López | 2.170 | 1882 | |
| 76 | Miguel Luna | 2.170 | 1879 | |
| 78 | Jorge Vélez# | 2.173 | 1893 | |
| 79 | Gaudencio Delgado | 2.175 | 1885 | |
| 80 | Juan Padilla | 2.177 | 1880 | |
| 81 | Zeferino Duque | 2.189 | 1884 | |
| 81 | Milcíades Gallegos | 2.189 | 1890 | |
| 83 | Gaudencio Delgado | 2.219 | 1887 | |
| 84 | Fernando Rodríguez | 2.229 | 1887 | |
| 85 | Flaminio Martínez | 2.233 | 1891 | |
| 86 | Beloveso Montoya | 2.240 | 1885 | |
| 87 | Rufino Escobedo | 2.250 | 1879 | |
| 88 | Constancio Álvarez# | 2.260 | 1885 | |
| 89 | Héctor López | 2.266 | 1878 | |
| 90 | Zeferino Duque | 2.267 | 1886 | |
| 91 | Juan Martínez# | 2.271 | 1890 | |
| 92 | Ignacio Barbosa | 2.272 | 1879 | |
| 93 | Jorge Vélez# | 2.276 | 1890 | |
| 94 | Gareth Morrison | 2.286 | 1884 | |
| 94 | Orocobix Peñafiel | 2.286 | 1878 | |
| 96 | Pío Martínez | 2.289 | 1888 | |
| 97 | Gaudencio Delgado | 2.291 | 1891 | |
| 98 | Juan Sanabria | 2.292 | 1878 | |
| 99 | Eugenio Mendoza# | 2.294 | 1891 | |
| 100 | Luis Mejía | 2.296 | 1879 |
