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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saavedra, Tobías | 2B | Spanish Town Knights | 26 | 04/05/1862 | Ponce | PUR | Right | Right | 178 cm | 84 kg | P222 |
| Sabatier, Raymond | 3B | Port-au-Prince Violettes | 26 | 01/19/1862 | Port-au-Prince | HAI | Switch | Right | 184 cm | 92 kg | P276 |
| Salinas, Britomaro | 1B | Cienfuegos Elefantes | 31 | 07/20/1857 | Yateras | CUB | Right | Right | 180 cm | 96 kg | P222 |
| Sanchez, Absalón | RP | Free Agent | 28 | 05/12/1860 | Las Marías | PUR | Left | Left | 180 cm | 84 kg | - |
| Sanchez, Esaú | 3B | Spanish Town Knights | 25 | 07/01/1863 | Monte Plata | DOM | Right | Right | 173 cm | 84 kg | P350 |
| Sanchez, Nerón | C | La Habana Rojos | 29 | 11/12/1858 | Las Tunas | CUB | Switch | Right | 168 cm | 82 kg | P233 |
| Sanchez, Wenceslao | SP | Port-au-Prince Violettes | 28 | 06/02/1860 | Corozal | PUR | Right | Right | 163 cm | 69 kg | P222 |
| Sandoval, Dorvid | 3B | Santo Domingo Leopardos | 30 | 04/05/1858 | Santa Clara | CUB | Right | Right | 173 cm | 86 kg | P222 |
| Santamaria, Jaime | RF | Marianao Frailes Grises | 31 | 08/09/1857 | Guisa | CUB | Left | Left | 169 cm | 80 kg | P222 |
| Santana, Flavio | SP | Free Agent | 26 | 02/11/1862 | La Antigua | MEX | Right | Right | 181 cm | 84 kg | - |
| Santry, Edward | 2B | Spanish Town Knights | 27 | 05/05/1861 | Chicago | USA | Right | Right | 178 cm | 83 kg | P233 |
| Scanlon, Pat J | LF | Saint-Marc Tempete | 27 | 03/25/1861 | Halifax | CAN | Left | Right | 183 cm | 82 kg | P300 |
| Scharf, Nick | LF | Cap-Haitien Colombes | 30 | 07/18/1858 | Baltimore | USA | Right | Right | 178 cm | 82 kg | P233 |
| Sera, Nepomuceno | CF | Marianao Frailes Grises | 28 | 01/21/1860 | Bayamo | CUB | Right | Right | 181 cm | 85 kg | P222 |
| Serpa, Herodes | SP | Almendares Alacranes | 26 | 09/07/1861 | Corralillo | CUB | Left | Right | 171 cm | 78 kg | P233 |
| Serrano, Gilberto | RF | Leogane Chevaux Rouges | 24 | 12/23/1863 | Ponce | PUR | Left | Left | 172 cm | 79 kg | P233 |
| Shaw, Lou | CF | La Habana Rojos | 25 | 10/13/1862 | Sandon | CAN | Left | Left | 177 cm | 78 kg | P860 |
| Siegel, John | 1B | Marianao Frailes Grises | 26 | 05/05/1862 | York | USA | Right | Right | 178 cm | 81 kg | P233 |
| Siffell, Frank | C | Almendares Alacranes | 27 | 05/05/1861 | Unknown | GER | Right | Right | 178 cm | 79 kg | P222 |
| Sisson, Bill | RF | Montego Bay Cobras | 31 | 02/07/1857 | Kingston | JAM | Switch | Left | 183 cm | 92 kg | P222 |
| Sixsmith, Ed | C | Montego Bay Cobras | 25 | 02/26/1863 | Philadelphia | USA | Right | Right | 175 cm | 65 kg | P233 |
| Sixtos, Ciro | RP | Cap-Haitien Colombes | 19 | 07/26/1869 | Chalchihiutan | MEX | Right | Right | 176 cm | 71 kg | - |
| Skinner, Al | CF | Montego Bay Cobras | 26 | 05/05/1862 | Unknown | USA | Right | Right | 178 cm | 82 kg | P233 |
| Sladen, Art | RF | Santo Domingo Leopardos | 27 | 10/28/1860 | Lowell | USA | Right | Right | 178 cm | 81 kg | P233 |
| Smith, Ed | CL | San Pedro de Macoris Guerreros | 26 | 05/05/1862 | Unknown | USA | Right | Right | 178 cm | 81 kg | P430 |
| Smith, Edgar E | CL | Santo Domingo Leopardos | 26 | 06/12/1862 | Providence | USA | Right | Right | 178 cm | 72 kg | P222 |
| Smith, Lewis | RF | Cienfuegos Elefantes | 30 | 05/05/1858 | Baltimore | USA | Right | Right | 178 cm | 78 kg | P222 |
| Smith, Pop | SS | Kingston Vultures | 31 | 10/12/1856 | Digby | CAN | Right | Right | 180 cm | 78 kg | P222 |
| Sosa, Marcial | SP | San Cristobal Caimanes | 24 | 09/05/1863 | Santo Domingo | DOM | Left | Right | 174 cm | 74 kg | P233 |
| Soto, Bernabé | CF | Almendares Alacranes | 26 | 02/23/1862 | Havana | CUB | Left | Right | 176 cm | 79 kg | P222 |
| Soto, Roque | 3B | Kingston Vultures | 29 | 10/21/1858 | San Juan | PUR | Right | Right | 174 cm | 83 kg | P233 |
| Stabell, Joe | 2B | Puerto Plata Delfines | 25 | 05/05/1863 | Buffalo | USA | Right | Right | 180 cm | 80 kg | P233 |
| Stanley, Joe | RF | Spanish Town Knights | 26 | 05/05/1862 | Unknown | USA | Right | Right | 178 cm | 82 kg | P222 |
| Stockwell, Len | CF | Leogane Chevaux Rouges | 30 | 08/25/1858 | Cordova | USA | Right | Right | 180 cm | 75 kg | P233 |
| Strauss, Joe | C | Montego Bay Cobras | 29 | 11/16/1858 | Cincinnati | USA | Right | Right | 175 cm | 80 kg | P640 |
| Suarez, Raimundo | 3B | Santo Domingo Leopardos | 28 | 11/13/1859 | Ponce | PUR | Left | Right | 172 cm | 81 kg | P820 |
