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| Friday, August 24th , 1888 |
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| RF Joshua Wagner retired from professional baseball. |
| Sunday, August 19th , 1888 |
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| Activated RF Harald Petersen from the injured list. |
| Saturday, June 30th , 1888 |
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| Placed RF Harald Petersen on the 10-day injured list. |
| Saturday, April 28th , 1888 |
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| Signed international amateur RF Nicholas Corfield out of Jamaica to a minor league contract. |
| Friday, April 13th , 1888 |
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| Signed international amateur SS Glen Molloy out of Jamaica to a minor league contract. |
| Saturday, March 3rd , 1888 |
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| Signed 1B Coach Travis Milson to a 3-year, P131 per year contract. |
| Wednesday, February 22nd , 1888 |
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| Signed free agent 1B Devin James to a minor league contract. |
| Monday, February 13th , 1888 |
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| Signed 3B Coach Martín Maldonado to a 3-year, P55 per year contract. |
| Monday, February 6th , 1888 |
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| Signed free agent SP Nicolás Feliz to a 1-year contract worth a total of P328. |
| Tuesday, January 31st , 1888 |
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| Signed Team Trainer Ken Dunn to a 4-year, P80 per year contract. |
| Monday, January 30th , 1888 |
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| Signed General Manager Adam Guffin to a 3-year, P481 per year contract. |
| Sunday, January 29th , 1888 |
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| SP Dionisio Cerna becomes a free-agent. |
| SP Tadeo Cuellar becomes a free-agent. |
| SP Ruy Gamez becomes a free-agent. |
| RP Benjamín Montenegro becomes a free-agent. |
| RP Brandon Mosby becomes a free-agent. |
| CL Sabino Armendariz becomes a free-agent. |
| C Justin Adams becomes a free-agent. |
| C Rodolfo Mendez becomes a free-agent. |
| C Mark Ransom becomes a free-agent. |
| C Dorvid Rice becomes a free-agent. |
| 1B Sam Campbell becomes a free-agent. |
| 1B Dwight Canning becomes a free-agent. |
| 1B Delfín Rijos becomes a free-agent. |
| 2B Emanuel Chico becomes a free-agent. |
| 2B Phil Moulds becomes a free-agent. |
| 2B Ethan Newman becomes a free-agent. |
| 2B Fabián Rosencranz becomes a free-agent. |
| 3B Rafael Alferez becomes a free-agent. |
| 3B Faro Garza becomes a free-agent. |
| SS Álvaro Carrasco becomes a free-agent. |
| SS Jayden Reese becomes a free-agent. |
| LF Wallace Goldman becomes a free-agent. |
| LF Labán Gutierrez becomes a free-agent. |
| CF Keith Jayne becomes a free-agent. |
| CF Roee Mendez becomes a free-agent. |
| RF Leo Figueroa becomes a free-agent. |
| SP Ralph Behan joins the team. |
| SP Tom Rowe joins the team. |
| C Dave Ditmars joins the team. |
| C Pete Hutchinson joins the team. |
| 2B Keith Ekdar joins the team. |
| SS Justin Campeau joins the team. |
| 2B Wyatt Laurendeau joins the team. |
| 1B Abel Smith joins the team. |
| 2B Luke Birley joins the team. |
| 3B Joe Lemay joins the team. |
| LF Vernon March joins the team. |
| LF Carl Aastrom joins the team. |
| RF Cole Harper joins the team. |
| CF Joe Osmond joins the team. |
| RF Joshua Wagner joins the team. |
| LF Rudy Richardson joins the team. |
